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Abstract:

Aim. Was to define prognostically meaningful ultrasound criteria for embologenic thrombus.

Materials and methods. 780 patients (800 limbs) with acute venous thrombosis were investigated; first group consisted of 370 patients with pulmonary embolism (PE) confirmed by lungs perfusion scintigraphic study; second group included 410 patients without PE. During ultrasound examination - 545 patients with floating thrombus were detected: 302 patients with PE (1st group) and 243 without PE (2nd group).

Results. In the first group (with PE) floating thrombus were detected in 79,5% of patients, in 20,5% of patients occlusive and nonocclusive thrombus were detected. It turned out that embologenic thrombus were localized more in shin veins (87,5%), popliteal vein (87,5%) and femoral vein (55,7%). Free floating thrombus had a form of elliptic paraboloid (60,1%), irregular form (67,9%), unechogenic structure with unechogenic contour (44,0%) or heterogenic structure with unechogenic contour (33,8%), high mobility (66,5%) (p>0,05). The length of thrombus was the same in both subgroups (p>0,05).

Conclusions. Floating trombus in 55,4% are embologenic, and are often localized in shin veins, popliteal vein and femoral vein. The absence of a floating pieces after PE indicates that occurred fragmentation of thrombus. It is found that embologenic thrombus often have a form of elliptic paraboloid. The length of thrombus can not be used as single criterion for thrombus's embologenic.  

 

Reference 

1.    Kinney T.B. Update on Inferior Vena Cava Filters. J. Vasc. Intem Radiol. 2003; 14(4) 425-440.

2.    Зубарев А.Р., Богачев В.Ю., Митьков В.В. Ультразвуковая диагностика заболеваний вен нижних конечностей. М.: Видар, 1999;104. Zubarev A.R., Bogachev V.Yu., Mit’kov V.V. Ulytrazvukovaya diagnostika zabolevaniy ven nizhnikh konechnostey [Ultrasound diagnostics of lower limbs’ veins diseases.]. M.: Vidar. 1999; 104 [In Russ].

3.    Харченко В.П., Зубарев А.Р., Котляров П.М. Ультразвуковая флебология. М.: Эники, 2005. 176. Kharchenko V.P., Zubarev A.R., Kotlyarov P.M. Ulytrazvukovaya phlebologia [Ultrasonic phlebology]. M.: Eniki, 2005;176 [In Russ].

4.    Чуриков ДА., Кириенко А.И. Ультразвуковая диагностика болезней вен. М.: Литтерра, 2011; 92. Churikov D.A., Kirienko A.I. Ulytrazvukovaya diagnostika bolezney ven [Ultrasound diagnostics of veins diseases ]. M.: Littera, 2011; 92 [In Russ].

5.    Kirienko A.I., Leontyev S.G., Lebedev I.S. Algoritm vedeniya bolynykh s ostrym venoznym trombosom [Algorythm of treatment tactics in patients with acute vein thrombosis]. Phlebohgiya. 2008; 1:58-62 [In Russ].

6.    Elliott C.G., Goldhaber S.Z., Jensen R.L. Delays in diagnosis of deep vein thrombosis and pulmonary embolism. Chest. 2005;128(5): 3372-3376.

7.    Goodacre S., Sutton A.J., Sampson F.C. Meta-analysis: the value of clinical assessment in the diagnosis of deep venous thrombosis. Ann. Intern. Med. 2005; 143(2): 129-139.

8.    Yablokov E.G., Kirienko A.I., Bogachev V.Yu. Khronicheskaya venoznaya nedostatochnosty [Chronic vein insufficiency]. M.: Bereg.1999; 127 [In Russ].

9.    Savelyev V.S. Phlebologiya. Rukovodstvo dlya vrachey. (Pod redaktsiey) [Phlebology. Medical quide]. M.: Meditsina 2001; 660 [In Russ].

10.  Baldridge E.D., Martin M.A., Welling R.E. Clinical significance of free-floating venous thrombi. J. Vasc. Surg. 1990; 11(1): 62-67.

11.  Norris C.S., Greenfield L.J., Herrmann J.B. Free-floating iliofemoral thrombus. A risk of pulmonary embolism. Arch. Surg. 1985;120(7): 806-808.

12.  Jones T.K., Barnes R.W., Greenfield L.J. Greenfield vena caval filter: rationale and current indications. Ann. Thorac. Surg. 1986; 42(6): 48-55.

13.  Berry R.E., George J.E., Shaver W.A. Free-floating deep venous thrombosis. A retrospective analysis. Ann. Surg. 1990; 211(6): 719-723.

14.  Baud J-M., Stephas L., Ribadeau-Dumas C. et al. Short- and medium-term duplex sonography follow-up of deep venous thrombosis of the lower limbs.J. Clin.Ultrasound. 1998; 26(1):-13.

15.  Anderson D.R., Kovacs M.J, Dennie C. et al. Use of spiral computed tomography contrast angiography and ultrasonography to exclude the diagnosis of pulmonary embolism in the emergency department. J. Emerg. Med. 2005; 29(4): 399-404.

16.  Rossiyskie klinicheskie rekomendatsii po diagnostike, lecheniyu i prophilaktike venoznykh tromboembolicheskikh oslozhneniy [Russian clinical recommendations for diagnostics, treatment and prophylaxis thrombotic complications of veins' diseases]. Phlebologiya. 2010; 1(2): 5-37 [In Russ].

  

Abstract:

Article presents the first successful experience of thrombolytic therapy in a patient with severe burns, complicated by pulmonary embolism. Article describes detailed analysis of tactics of treatment, with the help of foreign and domestic recommendtions. Analysis shows that in patient with burns in case of pulmonary embolism, thrombolytic therapy is a method of choice. 

 

References

1.     Trombojembolija legochnoj arterii. Kak lechit' i predotvrashhat' [Pulmonary embolism. How to treat and to prevent.] (Pod red. A.I. Kirienko, A.M. Chernjakovskogo, V.V. Andrijashkina). М.: MIA [MIA], 2015; 280 [In Russ].

2.     Konstantinides S.V., Torbicki A., Agnelli G. et al. 2014 ESC guidelines on the diagnosis and management of acute pulmonary embolism. Eur. Heart J. 2014; 35(43): 3033-3069, 3069a-3069k.

3.     Kearon C., Akl E.A., Comerota A.J. et al. Antithrombotic therapy for VTE disease: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American American College of Chest Physicians Evidence-Based Clinical Practice GuidelinesChest. 2012; 141 (2, Suppl): e419S- e494S.

4.     Rossijskie klinicheskie rekomendacii po diagnostike, lecheniju i profilaktike venoznyh trombojebolicheskih oslozhnenij. [Russian clinical recommendations on diagnostics, treatment and prophylaxis of venous thromboembolic complications.] Flebobgija. 2010; 1(2): 5-37 [In Russ].

5.     Bershtejn L.L. Trombojembolija legochnoj arterii: klinicheskie projavlenija i diagnostika v svete novyh rekomendacij Evropejskogo obshhestva kardiologov. [Pulmonary embolism: clinical presentation and diagnosis in the view of recommendations of the European Society of Cardiology] Kardiologija. 2015; 4: 111-119 [In Russ].

6.     Bershtejn L.L. Trombojembolija legochnoj arterii u pacienta so stabil'noj gemodinamikoj. [Pulmonary embolism in patients with stable hemodynamics]. Jeffektivnaja farmakoterapija. 2015; (24): 10-15 [In Russ].

7.     Charnaja M.A., Morozov Ju.A. Trombozy v klinicheskoj praktike. [Thrombosis in clinical practice]. М.: GJeOTAR-Media [GEOTAR Media], 2009; 224 [In Russ].

8.     Sibagatullin N.G., Zakirova I.A., Hatypov M.G. i dr. Ob jeffektivnosti tromboliticheskoj terapii pri lechenii trombojembolii legochnoj arterii v pozdnie sroki. [The effectiveness of thrombolytic therapy in the treatment of pulmonary embolism in later stages]. Kreativnaja onkologija i hirurgija. Jelektronnyj nauchno-prakticheskij zhurnal. 2013; 3: URL: http://eoncosurg.com/ob-effektivnosti-tromboliticheskojt [In Russ].

9.     Kurakina E.A. Sravnenie jeffektivnosti tromboliticheskoj i antikoaguljantnoj terapii geparinom pri trombojembolii legochnoj arterii promezhutochnogo riska. [Effectiveness of thrombolytic and anticoagulant therapy with in comparison with heparin in pulmonary embolism of intermediate risk]. Fundamental'nye issledovanija. 2012; 4(1): 69-731[In Russ].

10.   Kungurcev E.V., Mihajlov I.P., Kosolapov D.A. i dr. Sravnitel'nyj analiz lechenija bol'nyh s trombozami glubokih ven nizhnih konechnostej, oslozhnivshihsja TJeLA. Geparin ili trombolizis? [A comparative analysis of the treatment of patients with deep venous thrombosis of lower limbs, complicated by pulmonary embolism. Heparin or thrombolysis?]. Zhurnal im. N.V. Sklifosovskogo. Neotlozhnaja medicinskaja pomoshh'. 2012; 3: 25-28 [In Russ].

 

 

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